An Israeli publication has reported that if a new war breaks out with the Islamic Republic, Ayatollah Khamenei would be among the primary targets of attacks. Israel Hayom noted that any tensions could ignite a fresh conflict. Additionally, the Wall Street Journal quoted an Israeli official stating that Khamenei might be listed as a potential target. This official emphasized that Israel does not rule out any targets in its efforts to completely dismantle Iran's nuclear program.

The Israeli stance extends beyond just nuclear facilities; it aims to weaken the political and military power of the Iranian regime across various levels. This is the first time an Israeli official has publicly identified the Supreme Leader of Iran as a potential target in military operations.